abstract：OBJECTIVES:To determine whether X-ray, computed tomography (CT), bone scan, and clinical impression accurately reflect the level of vertebral fracture in patients about to undergo vertebroplasty. DESIGN:Retrospective observational study, utilizing patient inpatient notes, referral correspondence, and clinicians' priva...

journal_title：Journal of pain research

authors： Graziotti PJ,Graziotti CR,Sangster AM

更新日期：2013-05-10 00:00:00

abstract：BACKGROUND:It has been demonstrated that N-ethyl-lidocaine (QX-314) can target the transient receptor protein vanilloid 1 (TRPV1) nociceptors when coadministered with capsaicin, resulting in a selective block of the nociceptors. Capsaicin is problematic in therapeutic use because it induces firing of nociceptors. The p...

journal_title：Journal of pain research

authors： Nakagawa H,Hiura A

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Large interindividual differences in clinical responses to opioids and the variable susceptibility to abuse of this class of drugs make their use problematic. We lack a full understanding of the factors responsible for these differences. Dietary factors including methyl donor content have been noted to alter...

journal_title：Journal of pain research

authors： Liang DY,Sun Y,Clark JD

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Chronic low back pain (CLBP) and chronic neck pain (CNP) have become a serious medical and socioeconomic problem in recent decades. Patients suffering from chronic pain seem to have a higher prevalence of sleep disorders. PURPOSE:To calculate the prevalence of sleep deprivation in patients with CLBP and CNP...

journal_title：Journal of pain research

authors： Artner J,Cakir B,Spiekermann JA,Kurz S,Leucht F,Reichel H,Lattig F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the safety, tolerability, and preliminary efficacy of NGX-4010, a capsaicin 8% patch, following pretreatment with three different topical anesthetics in patients with peripheral neuropathic pain. METHODS:This open-label, multicenter study enrolled 117 patients with ...

journal_title：Journal of pain research

authors： Webster LR,Peppin JF,Murphy FT,Tobias JK,Vanhove GF

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Low back pain is often called nonspecific pain. In this type of low back pain, various emotions and stress are known to strongly affect pain perception. The purpose of this study is to investigate how the degree of low back pain changes in people with chronic mild low back pain when they are inside and outsi...

journal_title：Journal of pain research

authors： Sakakibara T,Wang Z,Kasai Y

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Detecting the efficacy of novel analgesic agents in neuropathic pain is challenging. There is a critical need for study designs with the desirable characteristics of assay sensitivity, low placebo response, reliable pain recordings, low cost, short duration of exposure to test drug and placebo, and relevant ...

journal_title：Journal of pain research

authors： Jenkins TM,Smart TS,Hackman F,Cooke C,Tan KK

更新日期：2012-01-01 00:00:00

abstract：:Phantom-limb pain (PLP) belongs among difficult-to-treat chronic pain syndromes. Treatment options for PLP are to a large degree implicated by the level of understanding the mechanisms and nature of PLP. Research and clinical findings acknowledge the neuropathic nature of PLP and also suggest that both peripheral as w...

journal_title：Journal of pain research

authors： Knotkova H,Cruciani RA,Tronnier VM,Rasche D

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To characterize the steady-state pharmacokinetic profile of hydromorphone extended-release (ER) in patients with chronic pain taking concomitant medications. METHODS:This open-label repeat-dose study enrolled 22 patients (mean age, 51.4 years; 81.8% female). All patients were receiving at least one concomita...

journal_title：Journal of pain research

authors： Vandenbossche J,Richarz U,Richards HM

更新日期：2012-01-01 00:00:00

abstract：:This open-label, phase 3b study (ClinicalTrials.gov Identifier: NCT00983073) evaluated the effectiveness, and tolerability of tapentadol for severe, chronic osteoarthritis knee pain that was inadequately managed with World Health Organization (WHO) Step I or II analgesics or co-analgesics, or that was not treated with...

journal_title：Journal of pain research

authors： Steigerwald I,Müller M,Kujawa J,Balblanc JC,Calvo-Alén J

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Sports-related injuries, such as sprains and strains, commonly occur during exercise and athletic events. Current therapy includes nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of upper gastrointestinal side effects. The present study assessed the efficacy and safety of the diclo...

journal_title：Journal of pain research

authors： Lionberger DR,Joussellin E,Lanzarotti A,Yanchick J,Magelli M

更新日期：2011-03-07 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess the attitudes of maternal health care providers to pain relief during labor in Zaria, Nigeria. METHODS:This was a multicenter, collaborative, cross-sectional pilot study of provider perspectives concerning pain relief during labor. A structured, self-administered, que...

journal_title：Journal of pain research

authors： Ogboli-Nwasor E,Adaji S,Bature S,Shittu O

更新日期：2011-01-01 00:00:00

abstract：:Temporal sensory summation of pain (TSSP) is a proxy measure of windup in humans and results in increased ratings of pain caused by a repetitive, low-frequency noxious stimulus. Aftersensations (ASs) are pain sensations that remain after TSSP has been induced. We examined the within-session and across-session variabil...

journal_title：Journal of pain research

authors： Alappattu MJ,Bishop MD,Bialosky JE,George SZ,Robinson ME

更新日期：2011-01-01 00:00:00

abstract：:Duloxetine is a serotonin-norepinephrine reuptake inhibitor approved by the US Food and Drug Administration for the treatment of fibromyalgia and painful diabetic neuropathy at doses of 60 mg daily. Duloxetine has been shown to significantly improve the symptoms of chronic pain associated with these disorders, as meas...

journal_title：Journal of pain research

authors： Wright A,Luedtke KE,Vandenberg C

更新日期：2010-12-16 00:00:00

abstract：OBJECTIVE:To evaluate the analgesic effectiveness of intra-articular botulinum toxin Type B (BoNT/B) in a murine model of chronic degenerative arthritis pain. METHODS AND MATERIALS:Chronic arthritis was produced in adult C57Bl6 mice by intra-articular injection of Type IV collagenase into the left knee. Following indu...

journal_title：Journal of pain research

authors： Anderson S,Krug H,Dorman C,McGarraugh P,Frizelle S,Mahowald M

更新日期：2010-09-06 00:00:00

abstract：:Adolescent low back pain (ALBP) is a common form of adolescent morbidity which remains poorly understood. When attempting a meta-analysis of observational studies into ALBP, in an effort to better understand associated risk factors, it is important that the studies involved are homogenic, particularly in terms of the ...

journal_title：Journal of pain research

authors： Milanese S,Grimmer-Somers K

更新日期：2010-05-17 00:00:00

abstract：:This paper reviews the current clinical data for the role of transdermal buprenorphine (BUP TDS) in the treatment of diverse acute and chronic pain syndromes. Literature searches were carried out using PubMed (1988 to June 2009). The published findings seem to support hypotheses regarding the rather unique analgesic m...

journal_title：Journal of pain research

authors： Hans G,Robert D

更新日期：2009-09-15 00:00:00

abstract：:Pain is the most common reason people visit emergency rooms. Pain does not discriminate on the basis of gender, race or age. The state of pain management in the emergency department (ED) is disturbing. ED physicians often do not provide adequate analgesia to their patients, do not meet patients' expectations in treati...

journal_title：Journal of pain research

authors： Motov SM,Khan AN

更新日期：2008-12-09 00:00:00